From biology to the clinic — exploring liver metastasis in prostate cancer
Here, the authors provide an overview of the epidemiological characteristics, prognosis, biological mechanisms, detection methods and treatment options for liver metastasis in prostate cancer.
Current issue
Rediscovering citrate as a biomarker for prostate cancer
- Lucas Galey
- Ayokunle Olanrewaju
- Étienne Audet-Walsh
Clinical Outlook
Gut microbiota influence bladder tumour development
- Louise Lloyd
Research Highlight
Intralesional heterogeneity on PSMA PET–CT predicts mCRPC outcomes
- Maria Chiara Masone
Research Highlight
The evolving treatment landscape of metastatic urothelial cancer
- Giandomenico Roviello
- Matteo Santoni
- Martina Catalano
Review Article
From biology to the clinic — exploring liver metastasis in prostate cancer
- Xudong Ni
- Yu Wei
- Yao Zhu
Review Article
Unlocking ferroptosis in prostate cancer — the road to novel therapies and imaging markers
- Pham Hong Anh Cao
- Abishai Dominic
- Elavarasan Subramani
Perspective
Contents
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ECR peer-review initiative
Nature Reviews Urology is committed to facilitating training in peer review and to ensuring that everyone involved in our peer-review process is appropriately recognised. We have, therefore, joined an initiative to allow and encourage established referees to involve one early-career researcher in our peer-review process.
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Racial disparities in prostate cancer in the UK and the USA: similarities, differences and steps forwards
Examination of racial disparities in prostate cancer in the USA and UK highlights systemic, socio-economic and sociocultural factors that might contribute to these differences. Understanding behavioural medicine might inform and improve the way in which the health-care system can engage with patients in minorities who are affected by this disease.
- Edward Christopher Dee
- Rebecca Todd
- Paul L. Nguyen
Review Article
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Interactions between androgen and IGF1 axes in prostate tumorigenesis
Feedback mechanisms between androgen and IGF1 signalling pathways have been linked to the development, progression and hormone refractoriness of prostate cancer. In this Review, the dynamic regulation of androgen and IGF1 signalling in prostatic epithelia and stroma are described and the implications for future preventative and therapeutic strategies are explored.
- Yao Mawulikplimi Adzavon
- Zoran Culig
- Zijie Sun
Review Article
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Plant-based diets and urological health
Here, the authors describe the evidence concerning plant-based dietary patterns and omnivorous diets with reduced consumption of animal-based food and increased consumption of plant-based foods and their associations with the most common urological cancers and benign urological conditions.
- Stacy Loeb
- James F. Borin
- Katherine Amin
Review Article
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Metaverse in surgery — origins and future potential
In this Perspective, the authors discuss our current knowledge of the use of the metaverse in surgery and its potential applications, highlighting challenges and opportunities. The ethical, legal and public health implications of integrating the metaverse into surgery are also discussed.
- Enrico Checcucci
- Alessandro Veccia
- Francesco Porpiglia
Perspective
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Measuring and improving the cradle-to-grave environmental performance of urological procedures
This Perspectives provides an overview of life-cycle assessment and its use in urological academic literature to date. The authors explain how life-cycle assessment can be interpreted and used to help to reduce the environmental impact of urology.
- Joseph B. John
- William K. Gray
- John S. McGrath
Perspective
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Urinary bladder transplantation in humans — current status and future perspectives
- Michał C. Czarnogórski
- Krzysztof Koper
- Jan Adamowicz
Perspective
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AI in prostate MRI: enhancing accuracy and reducing overdiagnosis
- Baris Turkbey
News & Views
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Human sperm RNA in male infertility
- Rossella Cannarella
- Andrea Crafa
- Aldo E. Calogero
Review Article
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PIONEER big data platform for prostate cancer: lessons for advancing future real-world evidence research
- Ailbhe Lawlor
- Katharina Beyer
- Ronald Herrera
Perspective
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20 yearsof ‘spilling the tea’ in urology
When Nature Clinical Practice Urology launched in 2004, we could not have foreseen the ways in which our field has transformed. As we celebrate our 20th anniversary — traditionally, the ‘china’ anniversary —it gives us a chance toget out the special china tea service, sit back with a cup of tea and reflect on what this journal, and the editors who work on it, have achieved.
Editorial
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Disulfidptosis-related genes could target personalized therapy and aid prognostics
- Annette Fenner
In Brief
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Source renewal is essential for mouse TIME models
- Annette Fenner
In Brief
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Nature Reviews Urology: evolving with the field for 20 years
For the past 20 years, Nature Reviews Urology has evolved alongside the field, reflecting a shift towards basic research as a tool to inform clinical practice. From the latest developments in urology to the advent of telehealth, the journal has remained committed to delivering rigorous and unbiased science, accessible to a global audience.
Editorial
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Looking backwards and looking forwards: the view from the middle
Over the past 20 years, Nature Reviews Urology has been at the forefront of developments in the field — from championing men’s health to explaining the intricacies of the prostate cancer tumour immune microenvironment. Going forwards the journal will continue to be a leader in the field, providing an important resource for patients and physicians alike.
Editorial
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Cell death score predicts prostate cancer metastasis and immunotherapy response
- Maria Chiara Masone
Research Highlight
